The levofloxacin concentration was assayed by high-performance liquid chromatography. A two-compartment pharmacokinetic model was used to estimate peak and total levofloxacin exposure. Elimination pharmacokinetics followed the anticipated pattern. However, breast-feeding mothers who take levofloxacin will expose their infants to levofloxacin in concentrations below those being studied in the pediatric population.
George M. However, amounts in breastmilk appear to be low and would not be expected to cause any adverse effects Chick gets fucked by horse breastfed infants. Levofloxacin may cause diarrhea, and in some cases it can be severe. If you have low blood potassium or an abnormally slow heartbeat, levofloxacin may Levaquin breast feeding your risk of having a Levaaquin, Levaquin breast feeding, or irregular heartbeat, feedlng of consciousness, or fainting spells. Filtered by:. Pharmacokinetics of three newer quinolones in pregnant and lactating women. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you.
Sucking breasts techniques. Levofloxacin
What Is Levaquin Levofloxacin? Theoretically, the calcium in breast milk might bind to Levaquin in the digestive tract of the infant, preventing the medication from being absorbed into the bloodstream this is why Levaquin should not be taken with calcium. Archived PDF from the original on 17 Topless haircut in washington DNA gyrase, on Levaquin breast feeding other hand, is responsible for supercoiling the DNA, so that it will fit in the newly formed cells. Levofloxacin secretion in Levaquin breast feeding milk: a case report. Common side effects include nauseadiarrheaand trouble sleeping. Sign In Site Map. Based on peak milk levels in this study, an exclusively breastfed infant would receive up to 0. Yes No. Views Read Edit View history. PMID: Levaquin Warnings and Precautions.
- Levofloxacin , sold under the trade names Levaquin among others, is an antibiotic.
- Medically reviewed by Drugs.
Drug information provided by: IBM Micromedex. Levofloxacin is used to treat bacterial infections in many different parts of the body. It is also used to treat anthrax infection after inhalational exposure. Levofloxacin is also used to treat and prevent plague including pneumonic and septicemic plague. Levofloxacin belongs to the class of medicines known as quinolone antibiotics.
It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of levofloxacin in children.
However, because of this medicine's toxicity, it should be used with caution, after other alternatives have been considered or found ineffective. Levofloxacin may be used in children 6 months of age and older to prevent anthrax infection after possible exposure, and to treat plague infection. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of levofloxacin in the elderly. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:. Take this medicine only as directed by your doctor. This medicine comes with a Medication Guide. Read and follow the instructions carefully.
Ask your doctor if you have any questions. Levofloxacin oral liquid should be taken 1 hour before or 2 hours after eating. Measure your dose with a marked measuring spoon, oral syringe, or medicine cup.
This medicine is best taken with a full glass 8 ounces of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help prevent some unwanted effects of levofloxacin.
This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses.
Also, it is best to take the doses at evenly spaced times, day and night. For example, if you are to take one dose a day, try to take it at the same time each day. If you need to take this medicine for anthrax infection or plague, your doctor will want you to begin taking it as soon as possible after you are exposed to anthrax or bacteria causing the plague.
If you are taking didanosine buffered tablets for oral suspension or the pediatric powder for oral suspension, sucralfate, or antacids, multivitamins, or other products containing aluminum, magnesium, iron, or zinc, take them at least 2 hours before or 2 hours after using levofloxacin.
These medicines may keep levofloxacin from working properly. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. It is very important that your doctor check your or your child's progress at regular visits to make sure the medicine is working properly and to decide if you should continue to take it.
Blood and urine tests may be needed to check for unwanted effects. If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor. Levofloxacin may rarely cause inflammation tendinitis or tearing of a tendon the cord that attaches muscles to the bones. This can occur while you are taking the medicine or after you finish using it.
Refrain from exercise until your doctor says otherwise. This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, hives, hoarseness, lightheadedness or fainting, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you or your child take this medicine.
Serious side effects can occur during treatment with this medicine. Sometimes serious side effects can occur without warning. However, possible warning signs include: black, tarry stools, blistering, peeling, or loosening of the skin, bloody or cloudy urine, chills, decreased urination, diarrhea, fever, joint or muscle pain, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips, severe stomach pain, skin rash, swelling of the face, fingers, feet, or lower legs, unusual bleeding or bruising, unusual weight gain, or yellow skin or eyes.
Check with your doctor immediately if you notice any of these warning signs. Levofloxacin may lower the number of some types of blood cells in your body. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured.
Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Levofloxacin may cause serious liver problems, including hepatitis.
Check with your doctor right away if you or your child start having nausea or vomiting, dark urine, light-colored stools, stomach pain, or yellow eyes or skin while using this medicine. Levofloxacin may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer.
If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor. Tell your doctor right away if you or your child start having numbness, tingling, or burning pain in the hands, arms, legs, or feet. These may be symptoms of a condition called peripheral neuropathy.
If you have low blood potassium or an abnormally slow heartbeat, levofloxacin may increase your risk of having a fast, slow, or irregular heartbeat, loss of consciousness, or fainting spells. If these symptoms occur, tell your doctor right away. Tell your doctor right away if you or your child have any of the following symptoms while using this medicine: convulsions seizures , feeling anxious, confused, or depressed, seeing, hearing, or feeling things that are not there, severe headache, trouble sleeping, or unusual thoughts or behaviors.
This medicine may increase your risk for aortic aneurysm bulge in the wall of the largest artery. Check with your doctor right away if you have sudden chest, stomach, or back pain, trouble breathing, cough, or hoarseness. If you are a diabetic patient using insulin or diabetes medicine by mouth: Levofloxacin may cause hypoglycemia low blood sugar in some patients.
Symptoms of low blood sugar must be treated before they lead to unconsciousness passing out. Different people may feel different symptoms of low blood sugar.
If you experience symptoms of low blood sugar, check with your doctor right away. Exposure to sunlight, even for brief periods of time, may cause severe sunburn or skin rash, redness, itching, or discoloration. When you begin using this medicine:. Levofloxacin may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally.
Do not drive or do anything else that could be dangerous until you know how this medicine affects you. If these reactions are especially bothersome, check with your doctor.
Levofloxacin is not efficiently removed by hemodialysis or peritoneal dialysis. OK Cancel. Levaquin is the brand name for levofloxacin, a prescription antibiotic drug used to treat a variety of bacterial infections, such as:. Use of levofloxacin is acceptable in nursing mothers with monitoring of the infant for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis thrush, diaper rash. Therefore, drugs that use that enzyme, like theophylline , do not interact with levofloxacin.
Levaquin breast feeding. Levofloxacin Breastfeeding Warnings
Of cases reported by the European Network of Teratology Information Services involving exposure to other fluoroquinolones, congenital malformations were reported in 4.
The risk of drug use during pregnancy is outweighed by the high fatality rates from these infections. Cartilage damage and arthropathy have been reported in immature animals of various species giving rise to concern over possible toxic effects on human fetal bone formation. Because safer alternatives are generally available, some experts consider fluoroquinolones contraindicated during pregnancy, especially during the first trimester.
LactMed: Use is considered acceptable with monitoring of the infant for possible effects on the gastrointestinal flora e. Excreted into human milk: Yes Comments : -This drug is the L-isomer S-enantiomer of ofloxacin, which is excreted into human milk. Cartilage erosion and arthropathy have been observed in immature animals giving rise to concern over toxic effects in the developing joints of nursing infants; however, some studies suggest risk is low.
Absorption of the small amounts of fluoroquinolones in milk may be blocked by the calcium in milk; data insufficient to prove or disprove. Postpartum time not specified , 10 lactating women received ofloxacin the racemic mixture mg orally every 12 hours for 3 doses. At 2 hours after the third dose, milk ofloxacin levels were highest and averaged 2.
Milk levels then declined and averaged 1. Based on peak milk levels in this study, an exclusively breastfed infant would receive up to 0. A woman received levofloxacin mg once a day IV for 9 days, then orally for 17 days ; 26 breast milk samples were collected, starting on day 10 of therapy and continuing for 6 days after therapy was stopped. Using a pharmacokinetic model, a peak milk level of 8. Milk levels declined with a half-life of 7 hours estimated ; at 65 hours after the dose, traces of this drug were still detectable in breast milk.
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Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. We comply with the HONcode standard for trustworthy health information - verify here. Skip to Content. Some people experience other serious and sometimes life-threatening reactions from taking Levaquin, such as:.
It's unknown if Levaquin can harm a developing fetus because no adequate and well-controlled studies have been carried out in pregnant women. However, the drug's antimicrobial benefits to the mother may outweigh the potential risks to her unborn child.
Levofloxacin is presumed to be present in breast milk, and the drug has the potential to cause serious side effects in infants. Other common side effects include yeast infections , vaginitis, severe itching, chest pain, and swelling from water buildup edema. Though rare, Levaquin can result in numerous serious side effects that may require medical attention, including:.
Additionally, children taking Levaquin may develop musculoskeletal disorders, such as arthritis and gait abnormalities. Make sure to tell your doctor about any medications, drugs, and supplements you take, especially steroid medications, anti-psychotic drugs, tricyclic antidepressants , diuretics , and heart-rate medications. Dosage and length of treatment differs depending on the type of infection that needs to be treated; adults with kidney problems, as well as children, must follow an adjusted treatment schedule.
According to animal studies, Levaquin is toxic in high doses, causing a number of muscular and nervous system symptoms, such as tremors, convulsions, and loss of control of bodily movements. Call your local poison control center or visit the nearest emergency hospital room if you've overdosed on Levaquin to have your stomach emptied. A: The average time it takes for Levaquin to completely be eliminated from the body ranges from 30 to 40 hours, essentially a day and a half to about two days, depending on the patient.
The reason for not overprescribing Medrol Dosepak methylprednisolone is to prevent the unwanted side effects from prolonged steroid use, including adrenal suppression and decreased ability to fight infection.
A: All medicines may cause side effects, but many people have no, or minor side effects. The duration of the side effect depends on the side effect you are experiencing. Consult your physician about the side effects you are experiencing.
Burton Dunaway, PharmD. A: Levaquin levofloxacin is a fluoroquinolone antibiotic which is used to treat many types of bacterial infections including urinary tract infection, and acute pyelonephritis kidney infection.
Those with rheumatoid arthritis are at increased risk of tendon rupture. This is not a complete list of the side effects associated with Levaquin. Laura Cable, PharmD. A: According to the prescribing information for Levaquin levofloxacin , myalgia muscle pain is listed as a possible side effect of the medication.
Also, Levaquin may cause severe tendon disorders, especially in people over 60 years of age. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis.
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Levofloxacin - InfantRisk Forums
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Click on an option below to access. Log out of ReadCube. At steady state, peak levofloxacin exposure in breast milk was 8. Elimination pharmacokinetics followed the anticipated pattern. Peak levofloxacin concentration in human breast milk is similar to levels attained in plasma.
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